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On November 11, 2004 Vice Chancellor Roberto Peccei issued a message to the UCLA community regarding the collective responsibility of faculty, staff, and administration for the ethical conduct of animal and human research. The letter focuses on the responsibilities of the Institutional Official, the Institutional Review Boards (IRBs), Chancellor’s Animal Research Committee (ARC), and the Office for Protection of Research Subjects (OPRS) for ensuring the protection of animal and human research subjects, facilitating the research mission of the University, and complying with Federal guidelines.